Active Ingredient: QUETIAPINE
Quetiapine blocks Ca2+ ICal channels. Normally, this would actually shorten the AP. It also blocks K+ channels (via hERG/IKr, Ito, and Iss channels) and the K+ blockade dominates, resulting in a prolonged QT interval
https://doi.org/10.1177/2045125313510194, https://doi.org/10.1016/j.ejphar.2024.176674, https://doi.org/10.1016/j.hrthm.2023.10.027