QTMeds

Drug Database Monograph

LERCAN 10 mg

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Active Ingredient: LERCANIDIPINE

QTc Interval Status:
neutre

Clinical Description (Database Summary)

(Hérité de LERCANIDIPINE VIATRIS 10 mg) Electrophysiological studies demonstrate that Lercanidipine does not block repolarizing potassium currents (IKr​, Ito​, or IK1​) and does not alter the action potential duration in human ventricular myocytes. Therefore, it is highly unlikely to cause QT interval prolongation in vivo and is considered safe regarding cardiac repolarization.

Scientific Sources / References

https://doi.org/10.1097/00005344-200011000-00007, https://doi.org/10.1016/S0011-393X(00)80031-4

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