Active Ingredient: ITRACONAZOLE
Itraconazole may not demonstrate direct, intrinsic QTc prolongation in the medical literature. However, it is a very potent CYP3A4 inhibitor and was reported in the litterature to prolong the QT interval when co-administered with QT-prolonging drugs (such as methadone, quinidine, amiodarone, and haloperidol), which can precipitate significant QTc prolongation and Torsades de Pointes.
https://doi.org/10.1007/s12281-014-0183-0, https://doi.org/10.1093/jac/dkw591