QTMeds

Drug Database Monograph

EBASTINE ARROW 10 mg

✓ VERIFIED BY DOCTOR

Active Ingredient: EBASTINE

QTc Interval Status:
inconnu

Clinical Description (Database Summary)

Precaution is recommended : QTc prolongation in guinea pigs, but supratherapeutic doses in humans doesn't prolong the QT interval (https://doi.org/10.1046/j.0306-5251.2001.01345.x) "Data obtained from >1000 patients enrolled in controlled trials also indicate that ebastine 10 or 20 mg/day is not associated with clinically significant changes in corrected QT (QTc) interval." (Hurst, M., Spencer, C.M. Ebastine. Drugs 59, 981–1006 (2000). https://doi.org/10.2165/00003495-200059040-00018)

Scientific Sources / References

https://doi.org/10.5114/pdia.2014.43191, https://pubmed.ncbi.nlm.nih.gov/8720305/, https://doi.org/10.1046/j.0306-5251.2001.01345.x, https://doi.org/10.2165/00003495-200059040-00018

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